Possibilities for Human Exposure to Aluminum
While the cause of Alzheimers disease is still for the most part unknown, one
environmental factor that has been suggested as playing a role in the disease is the chemical
element aluminum (Al). The third most abundant element in the Earth's crust, aluminum
exists mostly in the form of insoluble aluminosilicates and oxides1.
In addition to the many dietary sources of aluminum, such as cheese, beer2, antacid tablets, tea, toothpaste, infant formula, leaching of aluminum cookware,
drinking water3, and pharmaceutical products4, the
population is also exposed to aluminum by deodorants and with the possible inhalation of
aluminum and aluminosilicate dusts5. Much of the technology now
present in our society makes use of this light metal, "from beer cans to jetliners"6.
1 Fasman, G D., and Moore, C.D. "The solubilization of model Alzheimer tangles: Reversing the b-sheet conformation induced by aluminum with silicates." Proceedings of the National Academy of Sciences of the United States of America. 91 (1994): 11232- 11235. 2 Lovell, M.A. et al. "Laser Microprobe Analysis of Brain Aluminum in Alzheimers Disease." Annals of Neurology. 33 (1993): 36-42. 3 Massey, R.C., and Taylor, D. Aluminum in Food and the Environment. London: Chemistry Groups of the Royal Society of Chemistry, 1988. 4 Evans, Peter H. "Aluminum and Trace Element Oxidative Interactions in the Etiopathogenesis of Alzheimers Disease." 5 Galan, et. al 189 - FIND THIS! 6 Plambeck 1 ??!!!!
Jennifer McGilton
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