Home Mitosis Meiosis P53 Apoptosis Cancer History of Cancer Treatments Transgenic Mice Dox Treatment Future of Dox Credits

Oncogenes and Dox Treatment

This website is the creation of a group (identified as Group ) of University of Arizona Honors Biology 181H students. The main source for this web page appeared in the July 5th, 2002 issue of Science Magazine under the title Sustained Loss of a Neoplastic Phenotype by Brief Inactivation of MYC. The research was conducted at Stanford University and the University of California, San Francisco. The importance of the paper is the effect of a treatment that inactivated a specific oncogene, MYC, in transgenic mice. The first part of the paper is structured to show that the doxycycline (Dox) treatment the group was using caused tumor regression in the mice. The topic of the paper, and consequently this website, can be attributed to their faculty mentor, Margie Smith: Department of Biochemistry Biosciences West 337.

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Home Mitosis Meiosis P53 Apoptosis Cancer History of Cancer Treatments Transgenic Mice Dox Treatment Future of Dox Credits

Group Number 7

www.biology.arizona.edu/honors2002/group7/home07.htm

Last Updated: 12/5/02