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Arteriosclerosis- thickening of blood vessels leading to plaque formation and decreased blood flow.

Cardiomyopathy- a disease of heart muscle(http://education.yahoo.com/reference/dictionary/entry/)

Human Catalase- an enzyme produced by humans (although a variety of catalase exists in all organisms) which catalyze the breakdown of hydrogen peroxide to water and oxygen, thereby conferring protection to the cell from the toxicity of hydrogen peroxide.(http://www.ebi.ac.uk/interpro/potm/2004_9/Page1.htm)

Long Extension Polymerase Chain Reaction- Very similar to conventional polymerase chain reaction, with the exception of a longer extension time (the stage of PCR in which the polymerase adds bases to the growing copy).

Mitochondria- a organelle that is integral to energy production. It contains some of its own DNA that is separate from that of the cell.

Nucleus- double-membrane organelle that contains the chromosomes and the nucleolus.

Peroxisome- site of production and degradation of hydrogen peroxide, a toxic byproduct of cell metabolism.

Reverse Transcription Polymerase Chain Reaction (RT-PCR)- A technique used to transcribe an RNA strand into its DNA complement using reverse transcriptase, followed by amplification of the DNA product using conventional polymerase chain reaction.

Splenic Lymphoid Neoplasia- abnormal growth of cells found in the spleen, also known as a splenic tumor.  Refers to both benign and malignant growths.

Transgenic Mice- a mouse that is generated by a number of laboratory techniques, which  contains one or more altered gene(s) in every cell. This addition of genetic material can produce a gain or loss of function.

 

 


 

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University of Arizona
Biology 181H 2005 Group 7
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Last Revised: 12/7/05