mouse Glossary





The Debate




Arteriosclerosis- thickening of blood vessels leading to plaque formation and decreased blood flow.

Cardiomyopathy- a disease of heart muscle(

Human Catalase- an enzyme produced by humans (although a variety of catalase exists in all organisms) which catalyze the breakdown of hydrogen peroxide to water and oxygen, thereby conferring protection to the cell from the toxicity of hydrogen peroxide.(

Long Extension Polymerase Chain Reaction- Very similar to conventional polymerase chain reaction, with the exception of a longer extension time (the stage of PCR in which the polymerase adds bases to the growing copy).

Mitochondria- a organelle that is integral to energy production. It contains some of its own DNA that is separate from that of the cell.

Nucleus- double-membrane organelle that contains the chromosomes and the nucleolus.

Peroxisome- site of production and degradation of hydrogen peroxide, a toxic byproduct of cell metabolism.

Reverse Transcription Polymerase Chain Reaction (RT-PCR)- A technique used to transcribe an RNA strand into its DNA complement using reverse transcriptase, followed by amplification of the DNA product using conventional polymerase chain reaction.

Splenic Lymphoid Neoplasia- abnormal growth of cells found in the spleen, also known as a splenic tumor.  Refers to both benign and malignant growths.

Transgenic Mice- a mouse that is generated by a number of laboratory techniques, which  contains one or more altered gene(s) in every cell. This addition of genetic material can produce a gain or loss of function.





Transgenic Mice

Human Catalase

University of Arizona
Biology 181H 2005 Group 7
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Last Revised: 12/7/05