Arteriosclerosis- thickening of blood vessels leading to plaque formation and decreased blood flow.
Cardiomyopathy- a disease of heart muscle(http://education.yahoo.com/reference/dictionary/entry/)
Human Catalase- an enzyme produced by humans (although a variety of catalase exists in all organisms) which catalyze the breakdown of hydrogen peroxide to water and oxygen, thereby conferring protection to the cell from the toxicity of hydrogen peroxide.(http://www.ebi.ac.uk/interpro/potm/2004_9/Page1.htm)
Long Extension Polymerase Chain Reaction- Very similar to conventional polymerase chain reaction, with the exception of a longer extension time (the stage of PCR in which the polymerase adds bases to the growing copy).
Mitochondria- a organelle that is integral to energy production. It contains some of its own DNA that is separate from that of the cell.
Nucleus- double-membrane organelle that contains the chromosomes and the nucleolus.
Peroxisome- site of production and degradation of hydrogen peroxide, a toxic byproduct of cell metabolism.
Reverse Transcription Polymerase Chain Reaction (RT-PCR)- A technique used to transcribe an RNA strand into its DNA complement using reverse transcriptase, followed by amplification of the DNA product using conventional polymerase chain reaction.
Splenic Lymphoid Neoplasia- abnormal growth of cells found in the spleen, also known as a splenic tumor. Refers to both benign and malignant growths.
Transgenic Mice- a mouse that is generated by a number of laboratory techniques, which contains one or more altered gene(s) in every cell. This addition of genetic material can produce a gain or loss of function. |