Title- Restriction of DNA Replication to the Reductive Phase of the Metabolic Cycle Protects Genome Integrity

Intro

 

Introduction

The eukaryotic cell cycle, mitosis, is a succession of events that occur for the reproduction and growth of these multi-cellular organisms. Characteristic events in mitosis can divide the cell cycle into different stages, or phases. This website focuses on the interphase of cell cycle, which is when DNA replication occurs, and the cell is engaged in metabolic activities to prepare itself for cell division. The idea that these two processes are related arises much controversy in what their relation is exactly. A few theories propose that the cell cycle dictates DNA replication, whereas others support that DNA replication dictates the cell cycle. However, more research on yeast cells have determined that some unknown mechanisms link these two processes together. The experiment did not find conclusive evidence that either one of the processes controls the action of the other.


 

This web page was made possible by:
The University of Arizona,
The 181 Honors Biology Department,
along with the help of Dr. Tsu- Shuen-Tsao.  


University of Arizona:
www.arizona.edu
University of Arizona Biology 181 Honors: http://www.blc.arizona.edu/courses/181h/
Dr. Tsu- Shuen-Tsao’s Web Page: http://www.biochem.arizona.edu/dept/ppl/Profiles/tsao.htm

View the Paper Online: http://www.sciencemag.org/cgi/content/full/316/5833/1916/)